Search | Virtual Health Library

1.

Venetoclax and dinaciclib elicit synergistic preclinical efficacy against hypodiploid acute lymphoblastic leukemia.

Pariury, Holly; Fandel, Joshua; Bachl, Stefanie; Ang, Kenny K; Markossian, Sarine; Wilson, Chris G; Braun, Benjamin S; Popescu, Bogdan; Wohlfeil, Margo; Beckman, Kyle; Xirenayi, Simayijiang; Roy, Ritu P; Olshen, Adam B; Smith, Catherine; Arkin, Michelle R; Loh, Mignon L; Diaz-Flores, Ernesto.

Haematologica ; 108(5): 1272-1283, 2023 05 01.

Article in English | MEDLINE | ID: mdl-36700399

2.

Venetoclax in combination with chemotherapy as treatment for pediatric advanced hematologic malignancies.

Marinoff, Amanda E; Aaronson, Kathryn; Agrawal, Anurag K; Braun, Benjamin S; Golden, Carla; Huang, Benjamin J; Michlitsch, Jennifer; Southworth, Erica; Thrall, Allyson; Vo, Kieuhoa T; Stieglitz, Elliot.

Pediatr Blood Cancer ; 70(6): e30335, 2023 06.

Article in English | MEDLINE | ID: mdl-37036306

3.

Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia.

Stieglitz, Elliot; Troup, Camille B; Gelston, Laura C; Haliburton, John; Chow, Eric D; Yu, Kristie B; Akutagawa, Jon; Taylor-Weiner, Amaro N; Liu, Y Lucy; Wang, Yong-Dong; Beckman, Kyle; Emanuel, Peter D; Braun, Benjamin S; Abate, Adam; Gerbing, Robert B; Alonzo, Todd A; Loh, Mignon L.

Blood ; 125(3): 516-24, 2015 Jan 15.

Article in English | MEDLINE | ID: mdl-25395418

4.

The EBF1-PDGFRB T681I mutation is highly resistant to imatinib and dasatinib in vitro and detectable in clinical samples prior to treatment.

Tran, Thai Hoa; Nguyen, Jonathan V; Stecula, Adrian; Akutagawa, Jon; Moorman, Anthony V; Braun, Benjamin S; Sali, Andrej; Mullighan, Charles G; Shah, Neil P; Dai, Yunfeng; Devidas, Meenakshi; Roberts, Kathryn G; Smith, Catherine C; Loh, Mignon L.

Haematologica ; 106(8): 2242-2245, 2021 08 01.

Article in English | MEDLINE | ID: mdl-33626861

5.

Targeting oncogenic Ras signaling in hematologic malignancies.

Ward, Ashley F; Braun, Benjamin S; Shannon, Kevin M.

Blood ; 120(17): 3397-406, 2012 Oct 25.

Article in English | MEDLINE | ID: mdl-22898602

6.

Aurora Kinase A inhibition enhances DNA damage and tumor cell death with ¹³¹I-MIBG therapy in high-risk neuroblastoma.

Kumar, Prerna; Koach, Jessica; Nekritz, Erin; Mukherjee, Sucheta; Braun, Benjamin S; DuBois, Steven G; Nasholm, Nicole; Haas-Kogan, Daphne; Matthay, Katherine K; Weiss, William A; Gustafson, Clay; Seo, Youngho.

Res Sq ; 2024 Jan 18.

Article in English | MEDLINE | ID: mdl-38313265

7.

Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus.

Li, Qing; Haigis, Kevin M; McDaniel, Andrew; Harding-Theobald, Emily; Kogan, Scott C; Akagi, Keiko; Wong, Jasmine C Y; Braun, Benjamin S; Wolff, Linda; Jacks, Tyler; Shannon, Kevin.

Blood ; 117(6): 2022-32, 2011 Feb 10.

Article in English | MEDLINE | ID: mdl-21163920

8.

Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells.

Chan, Gordon; Cheung, Laurene S; Yang, Wentian; Milyavsky, Michael; Sanders, Ashley D; Gu, Shengqing; Hong, Wan Xing; Liu, Aurora X; Wang, Xiaonan; Barbara, Mary; Sharma, Tarun; Gavin, Joehleen; Kutok, Jeffery L; Iscove, Norman N; Shannon, Kevin M; Dick, John E; Neel, Benjamin G; Braun, Benjamin S.

Blood ; 117(16): 4253-61, 2011 Apr 21.

Article in English | MEDLINE | ID: mdl-21398220

9.

Mutant Ikzf1, KrasG12D, and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents.

Dail, Monique; Li, Qing; McDaniel, Andrew; Wong, Jason; Akagi, Keiko; Huang, Ben; Kang, Hio Chung; Kogan, Scott C; Shokat, Kevan; Wolff, Linda; Braun, Benjamin S; Shannon, Kevin.

Proc Natl Acad Sci U S A ; 107(11): 5106-11, 2010 Mar 16.

Article in English | MEDLINE | ID: mdl-20194733

10.

Oncogenic Kras initiates leukemia in hematopoietic stem cells.

Sabnis, Amit J; Cheung, Laurene S; Dail, Monique; Kang, Hio Chung; Santaguida, Marianne; Hermiston, Michelle L; Passegué, Emmanuelle; Shannon, Kevin; Braun, Benjamin S.

PLoS Biol ; 7(3): e59, 2009 Mar 17.

Article in English | MEDLINE | ID: mdl-19296721

11.

The sum is greater than the FGFR1 partner.

Braun, Benjamin S; Shannon, Kevin.

Cancer Cell ; 5(3): 203-4, 2004 Mar.

Article in English | MEDLINE | ID: mdl-15050910

12.

Nf1 and Sh2b3 mutations cooperate in vivo in a mouse model of juvenile myelomonocytic leukemia.

Morales, Carolina E; Stieglitz, Elliot; Kogan, Scott C; Loh, Mignon L; Braun, Benjamin S.

Blood Adv ; 5(18): 3587-3591, 2021 09 28.

Article in English | MEDLINE | ID: mdl-34464969

13.

KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice.

Wong, Jasmine C; Perez-Mancera, Pedro A; Huang, Tannie Q; Kim, Jangkyung; Grego-Bessa, Joaquim; Del Pilar Alzamora, Maria; Kogan, Scott C; Sharir, Amnon; Keefe, Susan H; Morales, Carolina E; Schanze, Denny; Castel, Pau; Hirose, Kentaro; Huang, Guo N; Zenker, Martin; Sheppard, Dean; Klein, Ophir D; Tuveson, David A; Braun, Benjamin S; Shannon, Kevin.

JCI Insight ; 5(21)2020 11 05.

Article in English | MEDLINE | ID: mdl-32990679

14.

KIT's ship comes in.

Braun, Benjamin S.

Blood ; 120(13): 2541-2, 2012 Sep 27.

Article in English | MEDLINE | ID: mdl-23019203

15.

Targeting Ras in myeloid leukemias.

Braun, Benjamin S; Shannon, Kevin.

Clin Cancer Res ; 14(8): 2249-52, 2008 Apr 15.

Article in English | MEDLINE | ID: mdl-18413813

16.

Bcl-2 Is a Therapeutic Target for Hypodiploid B-Lineage Acute Lymphoblastic Leukemia.

Diaz-Flores, Ernesto; Comeaux, Evan Q; Kim, Kailyn L; Melnik, Ella; Beckman, Kyle; Davis, Kara L; Wu, Kevin; Akutagawa, Jon; Bridges, Olga; Marino, Roberta; Wohlfeil, Margo; Braun, Benjamin S; Mullighan, Charles G; Loh, Mignon L.

Cancer Res ; 79(9): 2339-2351, 2019 05 01.

Article in English | MEDLINE | ID: mdl-30862722

17.

Tissue-Specific Oncogenic Activity of KRAS^A146T.

Poulin, Emily J; Bera, Asim K; Lu, Jia; Lin, Yi-Jang; Strasser, Samantha Dale; Paulo, Joao A; Huang, Tannie Q; Morales, Carolina; Yan, Wei; Cook, Joshua; Nowak, Jonathan A; Brubaker, Douglas K; Joughin, Brian A; Johnson, Christian W; DeStefanis, Rebecca A; Ghazi, Phaedra C; Gondi, Sudershan; Wales, Thomas E; Iacob, Roxana E; Bogdanova, Lana; Gierut, Jessica J; Li, Yina; Engen, John R; Perez-Mancera, Pedro A; Braun, Benjamin S; Gygi, Steven P; Lauffenburger, Douglas A; Westover, Kenneth D; Haigis, Kevin M.

Cancer Discov ; 9(6): 738-755, 2019 06.

Article in English | MEDLINE | ID: mdl-30952657

18.

A Collaborative Model for Accelerating the Discovery and Translation of Cancer Therapies.

Maertens, Ophélia; McCurrach, Mila E; Braun, Benjamin S; De Raedt, Thomas; Epstein, Inbal; Huang, Tannie Q; Lauchle, Jennifer O; Lee, Hyerim; Wu, Jianqiang; Cripe, Timothy P; Clapp, D Wade; Ratner, Nancy; Shannon, Kevin; Cichowski, Karen.

Cancer Res ; 77(21): 5706-5711, 2017 11 01.

Article in English | MEDLINE | ID: mdl-28993414

19.

Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia.

Stieglitz, Elliot; Mazor, Tali; Olshen, Adam B; Geng, Huimin; Gelston, Laura C; Akutagawa, Jon; Lipka, Daniel B; Plass, Christoph; Flotho, Christian; Chehab, Farid F; Braun, Benjamin S; Costello, Joseph F; Loh, Mignon L.

Nat Commun ; 8(1): 2127, 2017 12 19.

Article in English | MEDLINE | ID: mdl-29259179

20.

Congenital leukemia cutis with subsequent development of leukemia.

Zhang, Inga Hofmann; Zane, Lee T; Braun, Benjamin S; Maize, John; Zoger, Seymour; Loh, Mignon L.

J Am Acad Dermatol ; 54(2 Suppl): S22-7, 2006 Feb.

Article in English | MEDLINE | ID: mdl-16427986

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